We're going for peak comic book human stats here, so his physicals will need to be nerfed to fit the bill, especially since he's enhanced in every area. All of the other characters have to sacrifice something to get another thing, like how Khan's guy is the biggest and strongest but also the slowest, or how Vordak's guy is fast and strong but doesn't have the mass he needs to utilize his full strength most effectively, or how my guy has speed and power, but less strength than Khan's or Vordak's guys. 

In conclusion, I'd say nerf his physicals by half, and remove the magical abilities (including mist form), for the duration of the fight (after all, we're here to focus on melee, not powers). That should put him slightly below the strength or speed based characters within their area of specialization, but slightly above them outside of it. Basically a jack of all trades, master of none type fighter.