From my notes: 
Artificial Humans: In a desperate attempt, the scientists went
against the churches wishes to create human life and developed
what are called Artificial Humans. Artificial humans were created in hopes to stabilize the population
and increase reproduction. Artificials were given the genes that
were eventually lost to natural humans over a course of time.
Due to little or absolutely no reproduction, women slowly lost 
their chest size and their hips became significantly smaller, 
making any successful conception that much harder to follow through
with. The artificial women turned out to be beautiful. Curvaceous bodies, small waists, and 
large hips.. The human women became jealous, and would force their female
slaves to wrap sheets around their waists to unflatter their figure as much
as possible. The artificial males, however, were a bit trickier. The scientists 
couldn't successfully recreate the male y chromosome, so most of the men that were 
born either died shortly after, or where left disfigured. Most of the time, depending
on the severity of disfigurement, the child would be abandoned or killed. If the
problems were mild, such as a missing limb, it would simply be replaced with 
mechanical parts. Both male and female artificial humans are looked down upon. 
They either become slaves, servants, city guards, or are outcast.
Artificial men and women, together cannot conceive, due to a genetic malfunction on
the mens behalf. And no noble woman would want their men even close to the artificial 
women due to jealously and the fact that 'Artificials aren't really humans' Both artificial males and females have finer skin tones, light hair, and incredibly pale eyes. These characteristics were scientifically implanted to create more diversity among the population.