It would be neat if all Xenomorph players were able to control an entire Hive. They would start as a Facehugger, find a suitable host, implant a Queen, burst, find a suitable nest, begin laying eggs, hatch more facehuggers, find more hosts, and slowly build up their swarm repeating this process. They would control and manage each individual Xenomorph.

Predators on the other hand could be part of the same clan, here to do whatever they need to do (hunt, clean-up, what have you). Or to make things interesting, they're from separate clans - here to hunt each other, or to compete against one another.

In PvP the Predators would attempt to control battles against the Xenomorphs. Xenomorphs would need to rely on stealth and surprise to overcome the Predators. In all cases, the Predators would probably have the upperhand due to their tech, but the Xeno characters have the advantage of multiple 'lives' - if one of their Xeno's die they still have their queen and the other drones.

I've always seen AVP as being one of those "quantity VS quality" scenarios, where Predators value quality and the Xenos value quantity. Also, not all Xeno's are drones and queens. I think Grid from the first AVP movie was some sort of advanced Xeno. Not sure what they're called, but the Queen gives them a bit more freedom so they're smarter; as an example, Grid was able to use cover to defend himself against Scar's plasma-caster, whereas the other Aliens couldn't process such an action and didn't take cover and were effectively killed.

If this was a future AVP roleplay, I wonder if a Bounty Hunter Hish would work. He doesn't care much for his clan nor his species, he works for whoever he needs to work for to acquire a massive amount of credits.