Anti-Humanist/Echinda, The problem with this concept is that meta-powers aren't even proven to be genetic, there is no "meta" gene so any kind of DNA splicing probably wouldn't work. Also self-regenerating cells don't led to sentient animals, an interesting concept but one that needs more than a handwave. You could have him genetically engineer superior animals but uplifting an animal should be pretty damn difficult. 

Also the guy has no subtlety. If a bunch of beasts randomly attacked the populace, they would probably be stomped. More so if they tried robbing a Military barracks, which would be almost impossible considering the new technology, training, and the fact that there are several military superhumans. An attack on a domestic base would have triggered a massive manhunt by the DSA which would probably have led to him being killed or thrown in jail. So... he needs to be a lot more subtle. 

Also Dungeon Master's power needs to explained. Is it 100% accurate Precognition? Because that kind of power would be god-mody and a no no