Hmmm. What sort of issue does Urzoth have that could be addressed with a sidequest? Crippling anxiety? Low self-confidence in social situations? Near-fanatical loyalty to friends that dips into self-destructiveness to make up for her perceived failings to defend them? A total lack of knowledge on how to deal with emotional or mental problems in a constructive, non-violent way? Clearly all of these issues have only one unfailing solution:

Ladies' Night. 

(Hide your breakable furniture, people of Falkreath)