Part of me also wishes House was still alive, or at least his securitrons. I've always wanted to see something like the Securitron Army vs. BoS & Commonwealth Androids in a large scale war. Ohh, the many Fallout-esque dreams and visions I hope come true if Fallout 4 is ever made. 

Part of me wants to create a threatening force of super mutant slavers migrated far from Vault 87 to the midwest or midnorth or midsouth, wherever is available. Led by a behemoth with an intelligence of 10, with these storm trooper esque super muties that can never seem to hit anything....and yes that is a joke.

EDIT: Holy shit a revelation came to me, and now I want to create something very detrimental to the storyline. Be right back, and than I'll post my idea and see what everyone thinks of it.