[quote=@mdk]
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For some. For others it will violate the single most important ethical law in medicine -- "First, do no harm." 

Now it's important to note -- human trials [i]do[/i] happen, on a volunteer basis. I was almost placed in one (ketamine brain drip to treat regional sympathetic dystrophy -- something I'm pretty sure I didn't even [i]have[/i], but they were perfectly eager to sign me up anyway). One in ten of the people who volunteered for that trial got some temporary relief; all of them got, you know, ketamine in their brains, and all the wonderful things that does. 

So. From a first-hand almost human lab rat -- no thanks, I'm good. The rules exist for several important reasons. Human experimentation is a smart thing to regulate, and we regulate it almost hard enough. If you fling wide that door, and if you're lucky enough to be a statistical outlier which actually [i]finds a cure for anything at all[/i], your panacea is made out of the shattered lives of everyone who got the shitty Drug 1.0. My advice is to take that energy you would have used on Mad Science, and instead use it to mow someone's lawn or take out their trash, or carry their groceries inside. Start with caring before you jump right to "curing at any and all costs."
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Human trial's do happen. These trials are basically one of the last steps of drug/medical developments and as I've said, they're usually only conducted when the drugs has an extremely low probability of causing harm to its user.

Your point is bringing up that openly allowing human experimentation would bring ruin to all or most of the lives that its committed on. But I digress, I'm not telling you to snatch people off the streets or anything of the sort. Rather, experiment on people whose lives are otherwise shit anyway. Take someone from a third world country, offer them prospects of food, lodging, money and the chance to make a difference in the world. You'll see very little people rejecting it. These are the people who are dying from hunger and suffering from fatal diseases/ailments that can easily be treated. Take Kwashiorkor for example. You let them take the experiment, they get the hope of living. You don't? They die anyway. 

As, I've said earlier, I don't mean for these experiments to be the inhumane over exaggerated stuff you see in films. Instead, I'm advocating reducing the stringent rules of human trials. Instead of a 0.01% risk threshold, change it to 90%.