[@Corvotius]
[b]STATS:[/b]
Deaths, 136
Items, 325
Mom kills, 44
Secrets, 127
Best streak, 2

So yeah... a lot of deaths. Many were from some of the challenges. Which I still need to complete half of them. The main tip I can offer is practice, and start off with Maggie, Lazarus or Azazel. Isaac actually starts at a disadvantage because of the D6. Reason being is that items have tiers and some of the good items like ipecac and brimstone are top tier along with the D6. I believe from memory if a top tier item turns up there's a lesser chance that another top tier will appear so with Isaac you've actually gotta work harder for your run.

Maggie has the yum heart, so that's a good health pickup. Lazarus has an extra life and has similar stats to Isaac. He also bleeds toxic blood if you use that life and are hit after that point, so for chasing enemies it can help. Azazel is different. No red hearts but can earn them, plus a short range brimstone and flight. First chest run I had was with Azazel as the brimstone worked wonders with dmg pickups.

BoI is one of those games that start off hard. For ages I struggled against Dingle and the Haunt, but after you memorize their patterns and work out how they prep their attacks they become a lot easier.

Hit me up if you want to know any particular details. I've played and watched hundreds of hours of play so I know many of the technical stuff and synergies. :sun