[quote=@Kal-El]
<Snipped quote by Blu>

It's possible. Tsunade's lineage, Yamato's lineage and Orochimaru's perfect technique can lead to more Senju. Not many but a few.
[/quote]

Yamato and Orochimaru would produce more people with the kekkei genkai probably but I wouldn't consider that true Senju lineage. Unless Tsunade had children or something, I think it's safe to say the Senju Clan is gone. The Wood Release could probably still be around.