[quote=@Awson]
Special items that you start with don't count against you finding any later on. Isaac is OP.

This includes Magdelene's Yum Heart and anything Eden might get.
[/quote]

maybe I'm getting mixed up with the original. The original had some funny effects and items. I remember dad's key never really worked how it was supposed to and when the item pool was exhausted all shit broke loose.