I'm also checking in. Also for the synths and super mutant thing… are we really debating realism in a setting with what are essentially orcs and sentient zombies? What's the harm if people want to play as those characters? It's a game. Also, while we know a lot about the fallout world, we certainly don't know everything and I think we have plenty of room to get creative with how certain groups have moved or formed. If someone has a reasonable explanation for why their character is the way they are then I don't think anyone can really tell them 'no you can't do that.' Unless they're the gm I suppose.