A note on the Sea of Glass: It's called that because there are large deposits of crystallized ichor there. I don't know what that would mean for anyone that sets up nearby (other than having a supply of it, and dealing with lots of ghuls and mutants that flock to the area because of it), so I'll leave the final say to someone else. I have a feeling though that anyone who sets up nearby may have to deal with [i]some[/i] level of ichor pollution in the water and in general. Maybe not enough that life is impossible, but enough that you'd need to exercise caution.