[@Indra] I would say it depends on what you'd like to do. Do you have a general story idea in your head, would you like this to be more Slice of Life, would you like certain players to be trusted with influential positions so they can invent and drive the plot, etc. Once you have that figured out, you can arrange a setting/setup that works for what you want.

PS- I almost want to bring back my Lancelot avy/sig combo just to spite you xD