We could probably use some kind of guerilla who plans to overthrow a magi led government, backed by an anti-magic political faction. It's a simple formula, really, but it provides a solid conflict for us to start with. I'd say a workplace... perhaps a university? As coworkers, of course. 

An university provides a platform where: 1. both of us would be in a same rank or job position regardless of magic, the only thing judged would be merit; 2. we'd have a direct link of the conflict, given the students and the political expressions they develop (openly anti-magic groups, the magician students banding together, etc.); 3. we'd get plenty of excuses to have a friendship, trips for the faculty professors, meetings and a common interest on knowledge of some area; 4. we could open a discussion on morality, science and societal issues. 

By the way, I love the title of this thread.