[quote=Invader Len]
So, wait.... If the stake in the heart halts his regenerative abilities... Then twisting it would kill him? I mean, it ain't pumpin blood, oxygen flow stops within 7 seconds, blood stops flowing immediately, I mean, a stake is pretty big, it's crush at least two chambers just by being there. All you'd have to do to destroy the rest of it it just, twist it a little bit, or even like a blender, just the force to turn a doorknob would sever the arteries and veins, crush the remaining chambers, and basically deflate it like a sad, little heart balloon.Not that I'm an expert of staking people... Or crushing hearts.... Except for that one time in freshman year... Sorry Samuel....
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Basically the idea is that his regeneration "halts" because it's working overtime to keep him alive without a functioning heart. If empowered by blood, he can still function, minus any of his regenerative abilities. If at baseline, he's made catatonic until his body fails from being unsustained. Once the stake is removed, his heart can actually heal itself and his body resumes normal functions.

I basically want a little "screw you" for anyone that thinks he can be treated like any old vampire; that human blood has its benefits as well as its weaknesses.