Canonically speaking the MK Elder gods would pimp slap the Sup Archangels something chronic from what I understand as their lore, but I'm not that versed in it to be honest - but you have obviously declared otherwise for your RP which is fine. However, too many crossovers as usual.

Just stick with two or three so that it can work well and coherently. So firstly do you want a supernatural, not just the tv series, but thematically speaking. Or are you going for a more science fantasy type RP. Once you can decide that it'll help you put something together that fits.