Hunters are humans who are aware of the supernatural and have a bias against them for one reason or another(Which should be explained in the History or Other section of the CS). They have necessary equipment(Silver, iron, Magic dampening cuffs or ties, etc.) the stuff needed to take down Supernaturals. Hunters usually Excel in one Supernatural type, but others know a lot about many.

Sooo, yeah, humans that are well equipped.