I play beer pong with non-mixed rum from time to time. It encourages me not to lose. It may or may not have been a terrible idea on a few occasions, but man, I fucking hate beer. >_>

Usually, most of my parties involved a bonfire and card games. Once, we did a murder mystery, which was kind of fun, but I wouldn't want to be a cop again. You're too busy trying to solve the case than getting shitfaced with your friends. 

Although, I did shoot the murderer from blank range with a paintball pistol without paint. This suddenly became a hilarious party trick as people were chasing around their freshly-wet buddies getting out of the pool with a cold blast of Co2. That was pretty hilarious, and by far nowhere near the most irresponsible thing we've done. That would be the 12 foot beach bonfire.