[quote=CirusArvennicus]
-san is your safe bet-chan is cutesy, and familiar-kun is more endearing, and familiar. A teacher becomes familiar and endeared with their students throughout years of working with them, which is why it is used there.-sama is reverent. "My lady"-dono is also reverent. More so?
[/quote]

If you use -dono, you are either a shopkeeper, or a samurai talking to someone they review as their feudal lord. -kun is only appropriate with boys and your inferiors [i]within an environment[/i] (sempai/kohai stuff, workplaces), -san is roughly equivalent to Mr. X if you go back a couple of decades in the Western world. -chan is young girls (and... maybe boys? not sure) up to teens, but definitely implies closeness. And yes, -sama is for those you respect.

That's what I remember, at least.