[quote=@Scarifar]
Well, there's always the power of AU's.
[/quote]

Wouldn't that take out the fun of it? I mean, if you use an AU to get around the rules of an established universe, that seems a lot less interesting than applying new stuff to it while still being within the confines of the established rules.

For example, a bomb that spreads Phazon would be a fairly devastating weapon, and also wouldn't be out of place at a forbidden zombie research facility like the Umbrella we're at, leading to Phazon afflicted mutants. Hell, Phazon Nemesis.
If you really need to enhance your characters, use one of the myriad of augments that don't require blatantly ignoring a franchise's canon. There's exosuits, gene therapy, and similar stuff from multiple games and shows you could use.