[quote=@Remipa Awesome]
Wow, so I guess the biggest trumps are Removing the head, Burning them, or wood chipper. Hmm, I know it may be too comedic but would a wood chipper be over kill?
[/quote]

Hmmm.... If you grind up a typical vampire into goo, I'm going to say it would kill them, unless of course they have hemokinesis or seriously godlike regeneration. Someone could probably help them to survive and grow their body back from cells, but... it would probably take a mad scientist and a biostasis cylinder or some such fancy tech.