[quote=@Revans Exile]
<Snipped quote by RogerD>

The Flash tv show has already established that Meta's exist who were no created by the explosion in Central City.
[/quote]

I know we only have one known to date (edit: this does not include Mirakuru), and I am sure there will be more - but these would be covered under mutants as we're including Marvel Cinematic Universe too.