I will go with 3, but here is a suggestion:

An Alien Race invades Earth and an epic battle causes destructive effects all throughout the world. The Humans, with the help of the superhuman community are able to win and drive the Aliens off-planet. But in a desperate attempt, the aliens release a final blow in the form of a virus that turns the Superhumans on each other. 

The Aliens escape (might return) and the superhumans are tearing at each other, under the effect of the virus, it gets messy and the most powerful ones cause catastrophic damages, nuke bombs kind of catastrophic.

The overpowered ones are killed, the virus slowly weakens and the superhumans awake to dead earth, humans despising them, chaos, and mutated Superhumans thay gone rogue. Also there is the imminent return of the Aliens.