[quote=@Zendrelax]
I meant over-all.  I had two hits on the weakness, each being at least 90.  After that, the math is simple.

And then there's the all-out-attacks.  Weaknesses are important.  *nods sagely*
[/quote]

2 Garus would've resulted in 226 actually. First Garu is a crit so 2.5x the damage and the second one would've automatically been 2.5x as long as it hits. Without an initial crit with the first Garu, damage would've been 203 with 2 Garus. As it stands, your crit Garu + All-Out Attack is still the strongest combo with a total of 242. So yes, for the beginning bosses, exploiting their weaknesses is the fastest way to a victory.