[@thewizardguy]

Dark Energon affects anything that exists. It's the blood of Unicron, and like its ... Generator ... Seeks to completely annihilate everything in comes into contact with.

There was an instance in Prime where a human was affected by Dark Energon. He lived  only because he was a main character. And they canceled it by adding Energon, which stabilized him.

[url]http://tfwiki.net/wiki/Dark_Energon[/url]