Also, he can be killed. His weaknesses are as follows.

Soul Destruction.
Complete body destruction.
Pionic mind-destroying attacks.
Sealing techniques.

However, in order to make it more legit, I've decided to throw in 'divine' powers as another weakness. Specifically good-alligned magical powers, stereotypical paladin shit. Also holy artifacts, magical things inherently alligned to 'good'. He is the eldest vampire, after all, and a great force of evil. And such artifacts shouldn't be all too hard to find for some of the more resourceful factions.