[quote=@Xeiyenreisha]
Mad King Machination Brron is not all that useful against Void End Dragon since the card has an effect that negates its effect and destroys it when it targets Dragon or Machine Type monsters on Tsukiko's side of the field.
[/quote]

The effect of 'Mad King' seems to be a blanket effect, meaning that because Void End Dragon's secondary effect is based around targeting, it wouldn't work.