There's one issue, though. 

[quote=@Dead Cruiser]
To tie together a bunch of different characters, perhaps the plot could involve some sort of supernatural contracting company that employs our characters? I've seen that done well.
[/quote]

I already [i]have[/i] an original setting like this. 

I mean, we could always just play it as 'WoD Lite.'

I just wanted to play in the WoD, heh.