[@fdeviant] [@Melonhead]

The way I usually saw it was like this: 

Metas were often man's attempt, either on purpose or by accident, to overcome nature's design. 
Mutants were often nature's way to alter and evolve due to circumstances, namely since both are pretty closely tied together.  

I looked up the definition over mutant which is basically this in the wiki:

[quote]In biology and especially genetics, a mutant is an organism or a new genetic character arising or resulting from an instance of mutation, which is a base-pair sequence change within the DNA of a gene or chromosome of an organism. The natural occurrence of genetic mutations is integral to the process of evolution. The study of mutants is an integral part of biology; by understanding the effect that a mutation in a gene has, it is possible to establish the normal function of that gene.[/quote]

In baseline, mutations are created by evolution which means the gene is there but not switched on or it is altered from its original creation. Meta, usually, felt more like it was Man's attempt to prove he was better than Nature and improve on what he saw was a flaw. Some times it was accidental and people were just tossed into chemicals, bitten by radioactive spiders, etc in comics which made them beyond human due to humans trying to improve on what natural life they were given. (granted, some chems were never stated why they were there.) 

I asked this because I was attempted to explore those small differences at some point as Gene Co will be creating a cure for Meta humans thanks to the virus that Rach has. It is able to rewrite and construct DNA, both triggering naturally existing genes that give humans abilities and with more human tampering can control what abilities manifest and denied. It stands to reason the virus could also be used to either temporary fix, alter or completely cease a meta human's abilitiesm turning them back into their original forms. Mutants, however, due to their DNA, and it being apart of them rather than man made, would be unaffected for the most part. 

After talking with Xer, in order to sort his origin story out, I considered the possibility that the mutant population would start to rise since the Meta's increase from the domes. Sort of like a world wide evolutionary event and might be fun to play out over time, though again this is a sandbox and everyone's thoughts differ over the subject of Metas and Mutants. So, pardon the ramble. xD