[quote=@VitaVitaAR]
No, um...

They are literally completely useless against anyone with a magitech weapon. They're so vastly outstripped that the best comparison I can make is using a butter knife against someone in a tank.

There ARE magitech ranged weapons that blow mundane guns out of the water in terms of effectiveness.
[/quote]

Basically, guns are thematically inappropriate to the anime-style RPG you're running. Perfectly understandable.

Don't worry about trying all-encompassing worldbuilding justifications. They only raise more questions.