Strange watched Wolf as she had brought the shadows to life, watching as they moved into the open wound. He looked to Riza who seemed unphased though looked to the monitor. He looked back to Wolf when she asked for his guidance. "Think of this as the game Operation. The shards must not touch the walls. This is considered a more patient method. The only method that can be done. Though be warned. Riza may not be aware of what is going on. The closer you get to her heart, the more will react and try to reject you." Strange warned. Guiding her through the rest. 

As Stephen warned. As Wolf would go deeper to get the shards. Riza had begun reacting, her fingers would flinch and twitch, her eyes moving under her lids, her face showing clear emotion of pain and discomfort. Strange rested a gentle hand on her forehead, his eyes closed as he too began to concentrate, but on Riza. Her breathing slowed and back to how it was before. Whatever he was doing was working.