Oh my freaking god it would be hysterical.

LOL Yoko having fun during open heart surgery. I can't even xDDD

So instead of Yoko being Mario and Botan being Peach, they exchange roles? Botan saves YOKO'S ass somehow? I think the opportunity will definitely arise later on! Either Goshikuro related or something of that nature that she does help him with, and it'll be great! Yoko and Botan as Legendary Bandit lovers? Ayyy, Bonnie and Clyde type shit, only with a far less depressing ending >.>