[@Kibaro]
Please ask for clarification whenever you need to. Just because I know what I mean doesn't mean you do. 
1. The mansion is open.
2. The experiments can start there or we can seek them out. Some know Dr. Whitney. Some dont. Where you start is up to you.
3. Yes Lily is in her father's office talking about those who haven't been closed. Yes she is crying and the door is closed.