[quote=@Techspert]
<Snipped quote by Inimical>

If I'm not misremembering, he can mess with the outside-Existence "stuff." I know that it doesn't interact well with matter and generally drives living organisms to insanity. I theorize that it has a deterioration effect on philotic connections, but I don't have a scientific basis for it yet.
[/quote]

Well, I've yet to hear about this "Isaac" individual, but if he can access interreality space and not be affected, then he at least has the potential to unlock full access to other realities.