Depends on what kind of anthros we're talking about. Are these creatures with human features due to science/evolution possibly with their own cultures and stuff based in the rest of the world, or allegorical/artistic creations that are just taken for granted as an existing being in this world? I have a lot of instances of the former in my repetoire, but I have trouble writing about/drawing anthropomorphic animals without going, "Wait a second, how did we get here? Why are they like this?" Granted, plain magic is always an acceptable answer, but still. They're all different, and they may be incongruous.