If it's cool, I'm thinking of mixing Kara's story a little to include some crisis and some animated series aspects. The major thing being that she came other earth and was essentially adopted by the Kents and lived with them in Smallville until finally moving to Metropolis at 20. Perhaps took up the moniker of Supergirl around 18 or 19 years old helping primarily around Smallville at first. I'm thinking that perhaps she's enrolled at Metropolis U as a student...