Yes and no. On one hand, I have a couple of worlds that serve as the central basis for 99% of my plots and characters. On the other, it's not much of a roleplay verse, as I tend to just develop it myself these days.

I also stick anything and everything that flops (and really, even video games count as plot and character content) into them, in one form or another. Always heavily adapted, but in the end, I don't care about flops. As long as I see material to work with, it will be worked with.