It wouldn't work too well, since it'd have to be very short, and mostly just end up being a bunch of people chatting it up while the werewolf just tries to be completely out of the way. 

Honestly, you could just do a Werewolf kind of story, where one or at most two players are werewolves, and other characters are going through their own personal dramas. Since the idea of a werewolf story going on in the background of a heavy personal drama is always pretty effective. Especially if Werewolf hunters get involved.