Adaptation of an actual comic story: either the JL episode 'For The Man Who Has Everything', or the two part animated movie they did for The Dark Knight Returns.

TV show based off of comic books: that's a tough one. Either the Spectacular Spider-Man or Batman The Animated Series, aka the two most common answers when asked this question.

E: Oh shit, almost forgot Batman Beyond. Fuck BTAS and Spectacular Spider-Man, that's my favorite for the latter category.