Admittedly, I've always been somewhat weirded out by the blue as a choice. Spider-Man seems like a character meant for red and black, because the majority of spiders seem to be black, with the red being evocative of black widow spiders.

Then again, it's always been strange that Batman wears a black and gray costume with yellow accents (hell, sometimes ditching the black altogether for blue) when the most common bats are brown. 

Whatever. Crazy animal-themed people and their color blindness.