I don't like the cliche of an ultra abusive experiment program. For example, the old "turn kids into super soldiers but then treat them like crap so they escape and now they're on the run" plot. The kids will get abused, beaten, killed, and generally get treated as though their lives are cheap.

The problem is that their lives can't possible be cheap. Even the most evil corporation or government black site would know these people are the end result of a whole lot of money being spent, money supplied by someone that expects a product to come out the other end. Not to say their wouln't be discipline and restricted freedoms, but most of the time it feels like the creators just treat them badly so the characters have an excuse to hate the antagonist and escape.