I second [@unicorgi]'s question!
What kind of vampiric lore will we be using? Something modern and romantic or ancient and monstrous? I've been fascinated with the latter lately, but it would be interesting to have both; younger vampires that blend in with humans, older vampires closer to monsters of myth, and the conflict that arises. There could be conflict about killing humans, hunting slayers, or living in secrecy. I've also always liked vampires with shifter powers.