Just brainstorming and throwing this out there. It could be interesting and attract a few people; it may not, and just slowly disappear form the front pages of the interest check section.
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Okay, here's the premise I have in mind. 

We already discussed the general plan so I'll review it real quick. This is a new age, but not a very good one. Luffy's reign as a pirate king was a silver age. No one has been able to fill his place. The new pirates are cynical, cruel and careless and a major threat. They have spilled from the Grand Line and into the 4 blues. The Marines are not what they used to be either. With Coby gone, the system has been decaying. Men have forgotten what it means to be just, honourable and awesome. It is time for a great clean up and the Marine have just the man for that. [Insert name Here] is an ambitious and devoted Admiral who wants to see the end of the pirate age once and for all. 
Piracy is to be eradicated. 

The PCs, you guys, will be competent marine captains (or something higher, still thinking) who will be gifted a random devil fruit, as well as a crew of fodders, but will be allowed to make an NPC as their helper/assistant/sidekick. A Tashigi to your Smoker kind of deal. If two players wish to pair up, I'm cool with that. 

You will also be given a ship which you will be allowed to customize as you go on. You will start in the four blues, and then move on to tackle the Grand Line itself. 

Completely whipping out piracy is technically impossible, but the Marines have a card up their sleeve. This'll be revealed later. Anyway, I also want to boost the level of technology. So we'll be having weird aircrafts and zeppelins will now be present; just imagine WWI stuff. Franky-tier tech will come out later.[/INDENT]
We can figure out the rest.