Power level is even an issue inside any particular series or show.  In Star Trek, the most powerful technology and ships are in the original series.  Every additional series they lower the technology level regardless of timeline.  In Star Wars Blaster Tech and other small arms were more powerful in the prequels.

Macross/Robotech is pure ridiculous compared to most.  A single Valkyrie can outfight tie fighters or colonial vipers ten or even twenty to one. 
 Yet, we still made it work in the past by choosing a lesser carrier from the franchise with fewer fighters and no "macross gun".

The one I would argue would just not be acceptable would be a Glorious Heritage class vessel from Andromeda.  Those things use more realistic technology, involving relativistic weapons and bombs that can annihilate entire solar systems.  (Yes... 40 of these suckers!)

Key concept though is we'll try and make it work.

[@sep]I hadn't realized I'd stolen my Star Trek fan fic name for that Uraga Class Carrier.  Now that I think about it.  I was trying for a better name but flubbed.  The name rather fit the captain but not the ship's purpose as a special forces, preemptive strike platform.