Probably. Especially early in the program when they were still trying to figure out how Anchors protected Empaths. When the program started they only knew anchors protected empaths but not how or why. The first few empaths that couldn't find anchors in their circle of family and friends were probably matched several times before they figured out how to match the pieces together to protect the empaths. Now they know it's mostly biological and look at chemicals and things to match sure the anchor balances the empath.