Personally, I'd have to throw my lot in with DnD simply because I don't have any experience in playing Pathfinder even though I have a huge stash of PDFs for it laying around somewhere. But, to honest, if I had the choice, I'd say neither. There's other systems I prefer much, much more than DnD (and, well, Pathfinder), and the mental burnout just by looking at places like RPG's tabletop section or Roll20 and mainly seeing DnD/Pathfinder games only adds to my preference. Yeah, they're popular, but not every game has to be one of those two.