[quote=@Crimson Flame]
So if I wanted to be Spider Man, would I have to be Peter Parker, or could it be an OC? :hmm
[/quote]

Yeah, that's fine. You could say the Terrigen gives him spider-like powers. There could be a spider in the tree above him in Central Park that drops down and bites him just before the fog rolls in or something. 

[quote=@role model]
I am interested. And I have never played a woman character but I want to rp Black Widow.
[/quote]

Since she is usually portrayed as a normal human, you have a blank canvas to create her powerset. I would recommend a dexterity-based mutation similar to Spider-Man, and in fact you could have her be near Crimson Flame's character and so they both get spider-like abilities and take spider-like names.