[quote=Leidenschaft]
I have two shitloads of mods. I don't know which one it could be, though. And, yea, I used to be able to run Skyrim with zero crashes...or, well, one in a blue moon. Now, it's just acting weird on me. I'm thinking of wiping everything and starting over. Talos knows that Mod Manager would appreciate getting a few mods uninstalled that are never used.
[/quote]

Yeah, you have a load conflict. I think there's a thing called BOSS or whatever where it tells you if all the mods are installed correctly and which ones may be causing issues and CTD issues. I had the same problem and figured it out over the course of an hour and a half of trial and error.