[@Andronicus23] House has lost significant power over the past five years. Benny disappeared with the platinum chip and with it any chance House had to claim Vegas as his own. He spends most of his time brooding in his tower. 

I don't really have any plans for House so if you want to be a Strip family and kill him off, go for it. I'm trying to leave certain regions, especially Vegas kind of open to players deciding which factions are there and in charge. So far you're the first person with an interest in one of those factions so you have almost complete freedom in deciding what New Vegas, especially the Strip looks like.