No, but you sound familiar and Cowgirl is a nickname given to me by a few friends on here, just wondering :) 

Are you referring to the Awakening as the last film? If so, I haven't seen it yet. I know, terrible, it's blasphemous, but it is what it is.
Your idea is interesting. However, if your character is on the run, you would be playing by yourself essentially. I know I didn't give very many details in the drunken first post, but the game play will start in the city. So, I think your character would be alright if she stayed in the city. 
I can see where some scientific testing would be beneficial, but, you're getting really close to a modern day werewolf in the sense of can't remember things while in form and then the regular wolf form. Remember, chronologically, we're starting at the beginning of the series. Candles were used as light, horse's are the main mode of transportation. 

I'm still not sure what kind of plot I am going for here, I've had a few ideas that sound nice in the beginning but hit a snag somewhere in the middle. I've got a lot of planning to do.